Effect of Baduanjin exercise intervention on cognitive function and quality of life in women with breast cancer receiving chemotherapy: study protocol of a randomized controlled trial

Abstract Background More than 50% cognitive impairment was reported by cancer patients before and after medical treatment. However, there are no effective interventions to manage the problem in women with breast cancer. This pilot study designed evaluate protective effect of Baduanjin exercise on function cancer-related symptoms early-stage undergoing chemotherapy. Method A single-blinded, randomized control trial designed. The will recruit 70 scheduled receive chemotherapy from Shanghai China. All participants be randomly assigned (1:1) supervised group (5 times/week, 30 min each time) or wait-list for 3 months. intervention evaluated outcome measures including subjective objective function, (fatigue, depression, anxiety), health-related quality life at pre-intervention (T0), 8 weeks (T1), 12 (T2). PCI score FACT-Cog as primary descriptively, while sizes 95% confidence intervals (CIs) calculated. collected data analyzed using an intention-to-treat principle linear mixed-effects modeling. Discussion is first clinical investigate whether have a positive role improving receiving If possible, potential non-pharmacological dysfunction promote survivorship care among survivors. Trial registration Chinese Clinical Registry (ChiCTR) ChiCTR2000033152 . Registered 22 May 2020